N-[5-(Diphenyl-phosphinoylmethyl)-4-(4-fluoro-phenyl)-6-isopropyl-pyrimdin-2-yl]-N-methyl- methanesulfonamide(Z8.3)

  • CAS：289042-10-0
  • purity：99%
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Quality products?make an important contribution to long-term revenue and profitability. N-[5-(Diphenyl-phosphinoylmethyl)-4-(4-fluoro-phenyl)-6-isopropyl-pyrimdin-2-yl]-N-methyl- methanesulfonamide(Z8.3) GMP Manufacturer Global Trade 289042-10-0 with Fast Delivery

1.What is the N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide ?

An intermediate in the production of Rosuvastatin (R700500) derivatives.

diphenylphosphinous acid methyl ester
4020-99-9

diphenylphosphinous acid methyl ester

N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide
147118-36-3

N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide

N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
289042-10-0

N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Conditions
Conditions Yield
N-[4-(4-fluorophenyl)-5-(hydroxymethyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide; With phosphorus tribromide; In acetonitrile; at 20 ℃;
diphenylphosphinous acid methyl ester; at 60 ℃;
86%
N-[5-(bromomethyl)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide
799842-07-2

N-[5-(bromomethyl)-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl]-N-methylmethanesulfonamide

Ethyl diphenylphosphinite
719-80-2

Ethyl diphenylphosphinite

N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
289042-10-0

N-(5-((diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

Conditions
Conditions Yield
In toluene; at 60 ℃; for 3h;
73%
at 90 - 100 ℃; for 9h;
73%
In toluene; at 100 ℃;
1.6 g

2.What is the CAS number for N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide ?

The CAS number of N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide is 289042-10-0.

More information of N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide 289042-10-0 are:

CAS?Number

289042-10-0

Density

1.322 g/cm3

Boiling Point

679.125 °C at 760 mmHg

Flash Point

364.522 °C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.625

PSA

98.42000

LogP

6.39680

Pka

-0.57±0.10(Predicted)

3.What are another words for N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide ?

Synonyms?for?N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide 289042-10-0:Methanesulfonamide,N-[5-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-;

4.What is the molecular formula of N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide?

The chemical formula of ?N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide is?C28H29FN3O3PS which containing 28 Carbon atoms,29 Hydrogen atoms,1 Fluorine atoms,3 Nitrogen atoms,3 Oxygen atoms,1 Phosphorus atoms and 1 Sulfur atoms,and the molecular weight of??N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide?is 537.595.

5.What is N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide (289042-10-0) used for?

InChI:InChI=1/C28H29FN3O3PS/c1-20(2)26-25(19-36(33,23-11-7-5-8-12-23)24-13-9-6-10-14-24)27(21-15-17-22(29)18-16-21)31-28(30-26)32(3)37(4,34)35/h5-18,20H,19H2,1-4H3

Relevant articles related to N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide:

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