Trt-butyl (4R-CIS)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate (D5)

  • CAS：154026-95-6
  • purity：99%
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Chinese Factory Supply Wholesale Trt-butyl (4R-CIS)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate (D5) 154026-95-6 with Cheap Price

  • Molecular Formula: C15H26O6
  • Molecular Weight: 302.368
  • Appearance/Colour: White or off-white solid powder 
  • Vapor Pressure: 0mmHg at 25°C 
  • Refractive Index: 1.436 
  • Boiling Point: 353.142 °C at 760 mmHg 
  • Flash Point: 150.334 °C 
  • PSA： 71.06000 
  • Density: 1.037 g/cm3 
  • LogP: 2.19150 

tert-Butyl (4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetate(Cas 154026-95-6) Usage

InChI:InChI=1/C15H26O6/c1-10(16)18-9-12-7-11(19-15(5,6)20-12)8-13(17)21-14(2,3)4/h11-12H,7-9H2,1-6H3/t11-,12+/m1/s1

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154026-95-6 Process route

1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate
124655-09-0,407577-54-2

1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

acetyl chloride
75-36-5

acetyl chloride

(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
154026-95-6

(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

Conditions
Conditions Yield
1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate; With pyridine; In dichloromethane; at 20 ℃; for 0.5h;
acetyl chloride; In dichloromethane; at 20 ℃; for 1h;
86%
With pyridine; In dichloromethane; at 20 ℃; for 0.5h;
15.9 g
sodium acetate
127-09-3

sodium acetate

(4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester
154026-94-5,521973-99-9,521974-00-5,521974-01-6

(4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester

(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester
154026-95-6

(4R-cis)-6-[(acetyloxy)methyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester

Conditions
Conditions Yield
With copper(l) chloride; In N,N-dimethyl-formamide; at 120 - 130 ℃; for 24h; Reagent/catalyst; Solvent;
97.6%
With tetrabutylammomium bromide; In N,N-dimethyl-formamide; at 120 ℃; for 4h; Solvent;
542.97 g

154026-95-6 Upstream products

  • 127-08-2
    127-08-2

    potassium acetate

  • 154026-94-5
    154026-94-5

    (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester

  • 144-55-8
    144-55-8

    sodium hydrogencarbonate

  • 77-76-9
    77-76-9

    2,2-dimethoxy-propane

154026-95-6 Downstream products

  • 124655-09-0
    124655-09-0

    1,1-dimethylethyl (4R-cis)-6-hydroxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate

  • 124752-23-4
    124752-23-4

    tert-butyl 2-[(4R,6S)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate

  • 147489-06-3
    147489-06-3

    (4R,6S)-(E)-{6-[2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-vinyl]-2,2-dimethyl-1,3-dioxan-4-yl}acetic acid tert-butyl ester

  • 380460-39-9
    380460-39-9

    [(4R,6S)-2,2-dimethyl-6-(1-phenyl-1H-tetrazol-5-ylsulfanylmethyl)[1,3]dioxan-4-yl]acetic acid tert-butyl ester

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