N-(4-Cyanophenyl)glycine(DG10)

  • CAS：42288-26-6
  • purity：99%
Inquiry

Details

Reliable factory customized supply N-(4-Cyanophenyl)glycine(DG10) 42288-26-6

  • Molecular Formula: C9H8N2O2
  • Molecular Weight: 176.175
  • Appearance/Colour: Off-white solid 
  • Vapor Pressure: 8.8E-09mmHg at 25°C 
  • Melting Point: 237 °C(dec.) 
  • Refractive Index: 1.593 
  • Boiling Point: 447.2 °C at 760 mmHg 
  • PKA: 3.81±0.10(Predicted) 
  • Flash Point: 224.3 °C 
  • PSA： 73.12000 
  • Density: 1.3 g/cm3 
  • LogP: 1.12778 

N-(4-CYANO-PHENYL)-GLYCINE(Cas 42288-26-6) Usage

Physical properties

N-(4-Cyanophenyl)glycine is a off-white Solid.

InChI:InChI=1/C9H8N2O2/c10-5-7-1-3-8(4-2-7)11-6-9(12)13/h1-4,11H,6H2,(H,12,13)

42288-26-6 Relevant articles

Computer-aid drug design, synthesis, and anticoagulant activity evaluation of novel dabigatran derivatives as thrombin inhibitors

Huang, Shanshan,Ren,Peng, Xiuxiu,Qian, Pingping,Meng, Lingwei

, (2019/07/05)

In this study, computer-aided drug desig...

Mechanosynthesis of sydnone-containing coordination complexes

Pétry, Nicolas,Vanderbeeken, Thibaut,Malher, Astrid,Bringer, Yoan,Retailleau, Pascal,Bantreil, Xavier,Lamaty, Frédéric

supporting information, p. 9495 - 9498 (2019/08/15)

N-Phenyl-4-(2-pyridinyl) sydnone was sho...

Multi-substituted 4-methyl ester derivative of amino benzonitrile trunk and its preparation and use

-

Paragraph 0096; 0102-0104, (2018/01/19)

The invention provides new ester derivat...

Design, synthesis, anticoagulant activity evaluation and molecular docking studies of a class of N -ethyl dabigatran derivatives

Ren, Weixin,Ren, Yujie,Wang, Shuai

, p. 148 - 159 (2016/05/24)

A class of N-ethyl dabigatran derivative...

42288-26-6 Process route

bromoacetic acid
79-08-3

bromoacetic acid

4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

(4-cyanophenyl)glycine
42288-26-6

(4-cyanophenyl)glycine

Conditions
Conditions Yield
In water; at 100 - 110 ℃; for 3h;
88%
In water; at 100 ℃; for 16h;
In water; at 20 - 100 ℃; for 16.4h;
In water; at 100 ℃; for 5h;
In water; at 100 ℃;
chloroacetic acid
79-11-8

chloroacetic acid

4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

(4-cyanophenyl)glycine
42288-26-6

(4-cyanophenyl)glycine

Conditions
Conditions Yield
In water; Reflux;
73%
In water; Heating / reflux;
58%
In water; Reflux;
47%
With water;

42288-26-6 Upstream products

  • 79-11-8
    79-11-8

    chloroacetic acid

  • 873-74-5
    873-74-5

    4-Aminobenzonitrile

  • 144656-11-1
    144656-11-1

    (4-cyanophenylamino)-acetic acid tert-butyl ester

  • 79-08-3
    79-08-3

    bromoacetic acid

42288-26-6 Downstream products

  • 194162-76-0
    194162-76-0

    7-[2-(4-Cyano-phenylamino)-acetylamino]-heptanoic acid tert-butyl ester

  • 948551-71-1
    948551-71-1

    3-({3-[2-(4-cyano-phenylamino)-acetylamino]-4-methylamino-benzoyl}-pyridin-2-yl-amino)-ethyl propanoate

  • 851679-98-6
    851679-98-6

    2-(4-cyano-phenylamino)-N-{2-[(S)-3-hydroxy-pyrrolidin-1-yl]-(S)-1-phenyl-ethyl}-N-methyl-acetamide

  • 851848-59-4
    851848-59-4

    (4-aminomethyl-phenylamino)-acetic acid

Related Products