3-I[[2-[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino] propionic acid ethyl ester (DG11)
- CAS：211915-84-3
- purity：99%
Details
Quality products?make an important contribution to long-term revenue and profitability. Factory Supply industrial standard 3-I[[2-[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino] propionic acid ethyl ester (DG11) 211915-84-3 In Stock
1.What is the 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester ?
Nonpeptide thrombin inhibitor intermediate.
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-
isopropyl 2?(4?cyanophenylamino)acetate
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amino}propanoate](/upload/2026/4/8787c605093945ec886aabf26fd349b6_50282545-1579-40f7-b0cc-f67ae4e603bb.png)
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212322-56-0
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate
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![3-[[[2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid ethyl ester](/upload/2026/4/7445b355975c49f99936f66017939971_a32f6753-6d21-4abc-a70f-46d42abc4f12.png)
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211915-84-3
3-[[[2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid ethyl ester
| Conditions | Yield |
|---|---|
|
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 10 - 35 ℃;
|
82%
|
-
-
42288-26-6
(4-cyanophenyl)glycine
-
-
212322-56-0
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate
-
-
211915-84-3
3-[[[2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propionic acid ethyl ester
| Conditions | Yield |
|---|---|
|
(4-cyanophenyl)glycine; ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
With
1,1'-carbonyldiimidazole;
In
Isopropyl acetate;
at 20 ℃;
for 4h;
With
acetic acid;
In
Isopropyl acetate;
for 2h;
Reflux;
|
95%
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
toluene;
at 50 ℃;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
toluene;
at 20 - 25 ℃;
Temperature;
|
93.97%
|
|
(4-cyanophenyl)glycine;
With
benzotriazol-1-ol; dicyclohexyl-carbodiimide;
In
N,N-dimethyl-formamide;
at 3 ℃;
for 1h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 6h;
Temperature;
Further stages;
|
91.1%
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
diethyl ether; dichloromethane;
at 40 ℃;
Inert atmosphere;
Reflux;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
diethyl ether; dichloromethane;
at 40 ℃;
With
acetic acid;
In
diethyl ether; dichloromethane;
at 50 - 60 ℃;
Solvent;
|
86%
|
|
(4-cyanophenyl)glycine;
With
pivaloyl chloride; triethylamine;
In
tetrahydrofuran;
at 0 - 10 ℃;
for 0.5h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
at 45 ℃;
for 2h;
Reagent/catalyst;
Temperature;
|
85%
|
|
(4-cyanophenyl)glycine;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.75h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
83%
|
|
|
61%
|
|
(4-cyanophenyl)glycine;
With
1,1'-Carbonyl-di-(1,2,4-triazole);
In
tetrahydrofuran;
at 35 ℃;
for 1 - 2h;
Industry scale;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
at 47 - 53 ℃;
for 6 - 7h;
Industry scale;
With
acetic acid;
In
acetic acid butyl ester;
at 85 - 90 ℃;
for 2.5h;
Industry scale;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
tetrahydrofuran;
for 0.75h;
Inert atmosphere;
Reflux;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
for 6h;
Reflux;
With
acetic acid;
for 1h;
Reflux;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
tetrahydrofuran;
at 50 - 55 ℃;
for 2h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
at 50 - 65 ℃;
for 50h;
Product distribution / selectivity;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
tetrahydrofuran;
for 0.666667h;
Inert atmosphere;
Reflux;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
for 7h;
Inert atmosphere;
Reflux;
With
acetic acid;
for 3h;
Reflux;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
toluene;
at 55 - 60 ℃;
for 2h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
toluene;
at 60 - 100 ℃;
for 6h;
|
|
|
(4-cyanophenyl)glycine; ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
With
1,1'-carbonyldiimidazole;
In
tetrahydrofuran;
at 25 ℃;
for 24h;
With
acetic acid;
In
ethyl acetate;
at 70 ℃;
for 12h;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
tetrahydrofuran;
at 50 - 55 ℃;
for 3h;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
tetrahydrofuran;
at 50 - 65 ℃;
for 52h;
With
acetic acid;
at 95 - 100 ℃;
for 5h;
|
300 g
|
|
(4-cyanophenyl)glycine;
With
Imidazole hydrochloride; 1,1'-carbonyldiimidazole;
In
dichloromethane;
at 45 - 50 ℃;
for 1h;
Inert atmosphere;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
dichloromethane;
at 45 - 50 ℃;
for 1h;
Inert atmosphere;
With
acetic acid;
In
ethyl acetate;
for 6h;
Temperature;
Solvent;
Time;
Inert atmosphere;
Reflux;
|
127 g
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
toluene;
at 25 - 60 ℃;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
toluene;
at 60 - 100 ℃;
for 6h;
|
|
|
(4-cyanophenyl)glycine;
With
1,1'-carbonyldiimidazole;
In
N,N-dimethyl-formamide;
at 10 - 50 ℃;
for 3h;
Large scale;
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate;
In
N,N-dimethyl-formamide;
for 12h;
Large scale;
With
acetic acid;
at 110 ℃;
for 5h;
Solvent;
Temperature;
Large scale;
|
2.What is the CAS number for 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester ?
The CAS number of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester is 211915-84-3.
More information of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester 211915-84-3 are:
|
CAS?Number |
211915-84-3 |
|
Density |
1.255 g/cm3 |
|
Boiling Point |
756.382 °C at 760 mmHg |
|
Flash Point |
411.245 °C |
|
PSA |
113.14000 |
|
LogP |
4.12508 |
|
Pka |
4.21±0.10(Predicted) |
3.What are another words for 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester ?
Synonyms?for?3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester 211915-84-3:Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido;
4.What is the molecular formula of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester?
The chemical formula of ?3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester is?C27H26N6O3 which containing 27 Carbon atoms,26 Hydrogen atoms,6 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight of??3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester?is 482.542.
5.What is 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester (211915-84-3) used for?
Relevant articles related to 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester:
|
Article |
Source |
|
Method for purifying dabigatran etexilate intermediate |
- Paragraph 0022-0026, (2020/03/23) |
|
Preparation method of dabigatran intermediate |
- Paragraph 0036; 0037, (2019/12/25) |
6.Buy 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester with the best price .
FOND EVER CO.,LIMITED is a quality supplier of 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester 211915-84-3.
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