Details
Quality products?make an important contribution to long-term revenue and profitability. Excellent chemical plant bulk supply (35)-3-[4-[(2-Chloro-5-iodophenyl)methl]phenoxy]tetrahydro-furan 915095-94-2
1.What is the (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan ?
(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran can be used as reactant/reagent in preparation of C-?aryl D-?glurofuranoside compounds useful as reference compounds in the quality control of gliflozin type medicine.
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915095-87-3
(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone
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![(3S)-3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran](/upload/2026/4/135819cbd1904f5792c0c5871c8a5e2e_d9d33258-028e-45be-863f-5f314b174b7a.png)
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915095-94-2
(3S)-3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran
| Conditions | Yield |
|---|---|
|
With
aluminum (III) chloride; 1,1,3,3-Tetramethyldisiloxane;
In
toluene;
at 0 - 23 ℃;
for 2.5h;
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93%
|
|
With
aluminum (III) chloride; sodium tetrahydroborate;
In
tetrahydrofuran;
for 5h;
Reflux;
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90%
|
|
With
triethylsilane; aluminum (III) chloride;
In
methanol;
at 25 ℃;
for 1h;
Reagent/catalyst;
Temperature;
Solvent;
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90.33%
|
|
With
potassium borohydride; trifluoroacetic acid;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 0.5h;
|
85%
|
|
With
1,1,3,3-Tetramethyldisiloxane;
aluminum (III) chloride;
In
toluene;
at 18 - 26 ℃;
for 2.5h;
|
82.6%
|
|
With
aluminum (III) chloride; 1,1,3,3-Tetramethyldisiloxane;
In
toluene;
at 18 - 26 ℃;
for 2.5h;
|
82.6%
|
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(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone;
With
aluminum (III) chloride; 1,1,3,3-Tetramethyldisiloxane;
In
toluene;
at 18 - 26 ℃;
for 2.5h;
Industry scale;
With
hydrogenchloride;
In
water; acetone;
at 20 - 51 ℃;
Industry scale;
|
82.6%
|
|
With
triethylsilane; boron trifluoride diethyl etherate;
In
dichloromethane; acetonitrile;
at 0 - 20 ℃;
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79%
|
|
With
triethylsilane; boron trifluoride diethyl etherate;
In
dichloromethane; acetonitrile;
at 5 - 10 ℃;
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76.2%
|
|
(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone;
With
dimethylethylsilane; boron trifluoride diethyl etherate;
In
acetonitrile;
at 10 - 20 ℃;
for 16h;
With
sodium hydroxide;
In
water; acetonitrile;
at 0 - 20 ℃;
Product distribution / selectivity;
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(S)-(2-chloro-5-iodophenyl)(4-((tetrahydrofuran-3-yl)oxy)phenyl)methanone;
With
sodium tetrahydroborate;
In
tetrahydrofuran;
at 20 ℃;
for 16h;
With
boron trichloride; trifluoroacetic acid;
In
dichloromethane; water;
at 0 - 20 ℃;
for 4h;
Product distribution / selectivity;
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(S)-3-(4-(5-iodo-2-aminobenzyl)phenoxy)tetrahydrofuran
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915095-94-2
(3S)-3-[4-[(2-chloro-5-iodophenyl)methyl]phenoxy]tetrahydrofuran
| Conditions | Yield |
|---|---|
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(S)-3-(4-(5-iodo-2-aminobenzyl)phenoxy)tetrahydrofuran;
With
hydrogenchloride; sodium nitrite;
In
water;
at -10 - 0 ℃;
for 2.5h;
With
hydrogenchloride; copper(l) chloride;
In
water;
at 20 - 80 ℃;
for 3h;
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75.2%
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2.What is the CAS number for (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan ?
The CAS number of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan is 915095-94-2.
More information of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan 915095-94-2 are:
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CAS?Number |
915095-94-2 |
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Density |
1.578±0.06 g/cm3 (20 oC 760 Torr) |
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Boiling Point |
476.0±45.0 °C(Predicted) |
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PSA |
18.46000 |
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LogP |
4.70310 |
3.What are another words for (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan ?
Synonyms?for?(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan 915095-94-2:(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran;(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan;(S)-3-(4-(2-chloro-5-iodobenzyl)phenoxy)-tetrahydrofuran;Empagliflozin Intermediate1;Empagliflozin II;Empagliflozin intermediate;查看更多英文别名
4.What is the molecular formula of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan?
The chemical formula of ?(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan is?C17H16ClIO2 which containing 17 Carbon atoms,16 Hydrogen atoms,1 Chlorine atoms,1 Iodine atoms and 2 Oxygen atoms,and the molecular weight of??(3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan?is 414.67.
5.What is (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan (915095-94-2) used for?
Relevant articles related to (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan:
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Article |
Source |
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Empagliflozin intermediate preparation method |
- Paragraph 0092-0101, (2020/02/08) |
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Dicyclic derivative of glucoside as well as preparation method and application of dicyclic derivative |
- Paragraph 0202; 0203; 0204, (2018/07/30) |
6.Buy (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan with the best price .
FOND EVER CO.,LIMITED is a quality supplier of (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (3S)-3-[4-[(2-Chloro-5-iodophenyl)methyl]phenoxy]tetrahydro-furan 915095-94-2.
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