(3R,4S,5R,6R)-3,4,5-Tris(trimethylsilyloxy)-6-(trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one

  • CAS：32384-65-9
  • purity：99%
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High Quality Chinese Factory supply 32384-65-9 (3R,4S,5R,6R)-3,4,5-Tris(trimethylsilyloxy)-6-(trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one We supply high quality (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one (CAS 32384-65-9), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one ?

(3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one is , while it's Molecular Formula is C18 H42 O6 Si4 . 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone is an antidiabetic agent and an intermediate of Dapagliflozin (D185370). 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone acts as a reagent in the synthesis of trans-cyclohexane-bearing C-glucose as sodium glucose co-transporter 2 inhibitors.

What is the CAS number for (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one ?

The CAS number of (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one is 32384-65-9.

More information of (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one 32384-65-9 are:

Synonyms

(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)tetrahydro-2H-pyran-2-one;2,3,4,6-tetrakis-O-trimethylsilyl-D-glucono-1,5-lactone;(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-(trimethylsilyloxymethyl)tetrahydropyran-2-one;

CAS?Number

32384-65-9

Molecular Formula

C18 H42 O6 Si4

Molecular Weight

466.87

Density

0.97

Boiling Point

417℃

Flash Point

171℃

HS CODE

2931900090

PSA

63.22000

LogP

4.42360

What is (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one (32384-65-9) used for?

It is usually used as the intermediate and raw material in the chemistry synthesis and pharmaceutical industry. Especially, this chemical has been widely used in the design and synthesis of sodium-glucose transporter inhibitors.1 For example, this substance can be employed as raw material in the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxylphenyl)methyl]phenyl]-D-glucitol, which is commonly known as Dapagliflozin that act as the sodium dependent glucose transporters for treating type 2 diabetes.2 Moreover, it can also function as the intermediate for synthesizing empagliflozin, which is a novel and selective sodium glucose co-transporter-2 inhibitor.3 In addition, canagliflozin, another sodium glucose co-transporter-2 inhibitor, can be obtained by utilizing this substance as the intermediate.4

Articles related to (3R,4S,5R,6R)-3,4,5-tris(triMethylsilyloxy)-6-((triMethylsilyloxy)Methyl)tetrahydro-2H-pyran-2-one:

Article

Source

SYNTHETIC ROUTES TO HIGHER-CARBON SUGARS. REACTION OF LACTONES WITH 2-LITHIO-1,3-DITHIANE

Horton, Derek,Priebe, Waldemar

, p. 27 - 42 (1981)

Synthesis method and application of 1-methyl glucose

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Paragraph 0024-0028, (2021/01/29)

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