Acetoxy empagliflozin

  • CAS：915095-99-7
  • purity：99%
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Quality products?make an important contribution to long-term revenue and profitability. Top Quality Chinese Factory supply 915095-99-7 Acetoxy empagliflozin

1.What is the (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol ?

Impurity of the drug Empagliflozin (E521510). From process for the preparation of glucopyranosyl-substituted benzonitriles for use as therapeutic agents treating metabolic disorders.

(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone
461432-22-4

(5-bromo-2-chlorophenyl)(4-ethyloxyphenyl)methanone

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate
915095-99-7

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate

Conditions
Conditions Yield
Multi-step reaction with 7 steps
1.1: potassium borohydride; methanol / tetrahydrofuran / 0 - 20 °C
2.1: hydrogenchloride / toluene; methanol / 65 - 70 °C
3.1: TurboGrignard / tetrahydrofuran / 0 - 5 °C / Inert atmosphere
3.2: 0 - 30 °C / Inert atmosphere
3.3: 40 - 50 °C
4.1: N-ethyl-N,N-diisopropylamine; dmap / dichloromethane / 0 - 20 °C
5.1: triethylsilane; boron trifluoride diethyl etherate / toluene / 0 - 20 °C
6.1: boron trifluoride diethyl etherate / dichloromethane / 0.5 h / Reflux
7.1: potassium carbonate / acetonitrile / 20 °C
With hydrogenchloride; methanol; triethylsilane; dmap; TurboGrignard; potassium borohydride; boron trifluoride diethyl etherate; potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane; toluene; acetonitrile;
Multi-step reaction with 7 steps
1.1: potassium borohydride; methanol / tetrahydrofuran / 0 - 20 °C
2.1: sulfuric acid / 65 - 70 °C
3.1: cyclohexylmagnesiumchloride / tetrahydrofuran / 0 - 5 °C / Inert atmosphere
3.2: 0 - 30 °C / Inert atmosphere
3.3: 40 - 50 °C
4.1: N-ethyl-N,N-diisopropylamine; dmap / dichloromethane / 0 - 20 °C
5.1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C
6.1: boron trifluoride diethyl etherate / dichloromethane / 0.5 h / Reflux
7.1: potassium carbonate / acetonitrile / 20 °C
With methanol; triethylsilane; dmap; potassium borohydride; sulfuric acid; boron trifluoride diethyl etherate; cyclohexylmagnesiumchloride; potassium carbonate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; acetonitrile;
(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone
915095-85-1

(5-bromo-2-chlorophenyl)(4-fluorophenyl)methanone

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate
915095-99-7

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-trityl triacetate

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1: potassium tert -butylate / tetrahydrofuran / 2 h / 0 - 10 °C
2: aluminum (III) chloride; potassium borohydride / tetrahydrofuran / 6 h / 20 °C
3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 8 h / 8 °C / Inert atmosphere
4: tetrakis(triphenylphosphine) palladium(0) ; potassium dihydrogenphosphate / toluene / 12 h / 105 °C
With aluminum (III) chloride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium dihydrogenphosphate; tetrakis(triphenylphosphine) palladium(0); potassium borohydride; potassium tert-butylate; potassium acetate; In tetrahydrofuran; 1,4-dioxane; toluene;

2.What is the CAS number for (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol ?

The CAS number of (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol is 915095-99-7.

More information of (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol 915095-99-7 are:

CAS?Number

915095-99-7

Density

1.33±0.1 g/cm3(Predicted)

Boiling Point

673.8±55.0 °C(Predicted)

PSA

132.89000

LogP

3.89660

3.What are another words for (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol ?

Synonyms?for?(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol 915095-99-7:(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol;Acetoxy Empagliflozin;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol tetraacetate

4.What is the molecular formula of (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol?

The chemical formula of ?(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol is?C31 H35 ClO11 which containing 31 Carbon atoms,35 Hydrogen atoms,1 Chlorine atoms and 11 Oxygen atoms,and the molecular weight of??(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol?is 619.065.

5.What is (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol (915095-99-7) used for?

(1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol is a complex organic compound with a unique chemical structure. It is a derivative of D-glucitol, a sugar alcohol, and features various functional groups, including acetoxy, chloro, and tetrahydrofuran moieties. (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol exhibits a high degree of structural complexity and specificity, making it a potentially valuable molecule for various applications in the pharmaceutical and chemical industries.

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6.Buy (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol with the best price .

FOND EVER CO.,LIMITED is a quality supplier of (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on (1S)-1,5-anhydro-2,3,4,6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl] methyl]phenyl]-D-Glucitol 915095-99-7.

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