O-Benzyl posaconazole

  • CAS：170985-86-1
  • purity：99%
Inquiry

Details

Quality products?make an important contribution to long-term revenue and profitability. Quality Factory Supply 99% Pure O-Benzyl posaconazole 170985-86-1 with Efficient Delivery

1.What is the O-Benzyl Posaconazole ?

Precursor to the fungicide, Posaconazole.

phenyl N-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)carbamate
184177-81-9

phenyl N-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)carbamate

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one
170985-86-1

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1.1: triethylamine / 1,4-dioxane / 24 h / 90 - 100 °C
2.1: sodium hydroxide / water; dimethyl sulfoxide / 0.75 h / 25 - 30 °C
2.2: 5 h / 25 - 30 °C
With triethylamine; sodium hydroxide; In 1,4-dioxane; water; dimethyl sulfoxide;
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / 1,4-dioxane / Large scale
1.2: 80 °C / Large scale
2.1: sodium hydroxide / dimethyl sulfoxide; water / Large scale
2.2: 25 °C / Large scale
With N-ethyl-N,N-diisopropylamine; sodium hydroxide; In 1,4-dioxane; water; dimethyl sulfoxide;
Multi-step reaction with 2 steps
1: triethylamine / acetonitrile / 30 h / 65 °C
2: sodium hydroxide / dimethyl sulfoxide; water / 20 - 50 °C
With triethylamine; sodium hydroxide; In water; dimethyl sulfoxide; acetonitrile;
2-[(1S,2S)-1-ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
184177-83-1

2-[(1S,2S)-1-ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

C<sub>20</sub>H<sub>19</sub>F<sub>2</sub>N<sub>3</sub>O<sub>4</sub>S

C20 H19 F2 N3 O4 S

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one
170985-86-1

4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-1H-1,2,4-triazol-5(4H)-one

Conditions
Conditions Yield
2-[(1S,2S)-1-ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.75h;
C20H19F2N3O4S; In dimethyl sulfoxide; at 50 ℃; for 5h;
85%

2.What is the CAS number for O-Benzyl Posaconazole ?

The CAS number of O-Benzyl Posaconazole is 170985-86-1.

More information of O-Benzyl Posaconazole 170985-86-1 are:

CAS?Number

170985-86-1

Density

1.30±0.1 g/cm3(Predicted)

Boiling Point

889.9±75.0 °C(Predicted)

PSA

104.70000

LogP

7.07020

Pka

6.49±0.40(Predicted)

3.What are another words for O-Benzyl Posaconazole ?

Synonyms?for?O-Benzyl Posaconazole 170985-86-1:O-Benzyl Posaconazole;2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol

4.What is the molecular formula of O-Benzyl Posaconazole?

The chemical formula of ?O-Benzyl Posaconazole is?C44H48F2N8O4 which containing 44 Carbon atoms,48 Hydrogen atoms,2 Fluorine atoms,8 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??O-Benzyl Posaconazole?is 790.913.

5.What is O-Benzyl Posaconazole (170985-86-1) used for?

Relevant articles related to O-Benzyl Posaconazole:

Article

Source

Synthetic method of high-purity posaconazole

-

Paragraph 0008; 0013-0015, (2020/12/31)

Preparation method of high-purity posaconazole

-

, (2019/06/27)

6.Buy O-Benzyl Posaconazole with the best price .

FOND EVER CO.,LIMITED is a quality supplier of O-Benzyl Posaconazole. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on O-Benzyl Posaconazole 170985-86-1.

Related Products