What is the D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-?

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- is , while it's Molecular Formula is C29H33ClO10. Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.

What is the CAS number for D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-?

The CAS number of D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- is 461432-25-7.

What is D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- (461432-25-7) used for?

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-, also known as Dapagliflozin Tetraacetate, is a derivative of Dapagliflozin, a sodium-glucose transporter 2 (SGLT2) inhibitor. D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)is characterized by its unique chemical structure, which includes a D-glucitol backbone with a 1,5-anhydro ring, a 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl group, and four acetate groups. It plays a crucial role in the regulation of glucose absorption in the body.

What is the D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-?

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- is , while it's Molecular Formula is C29H33ClO10. Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.

What is the CAS number for D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-?

The CAS number of D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- is 461432-25-7.

What is D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)- (461432-25-7) used for?

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)-, also known as Dapagliflozin Tetraacetate, is a derivative of Dapagliflozin, a sodium-glucose transporter 2 (SGLT2) inhibitor. D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, tetraacetate, (1S)is characterized by its unique chemical structure, which includes a D-glucitol backbone with a 1,5-anhydro ring, a 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl group, and four acetate groups. It plays a crucial role in the regulation of glucose absorption in the body.

Dapagliflozin

Your Location:Home > Dapagliflozin > (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Product classification

(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

CAS：461432-25-7
purity：99%

Inquiry

Details

Chinese Manufacturer Supply (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 461432-25-7 On Stock with Competitive Price

Molecular Formula: C29H33ClO10
Molecular Weight: 577.028
Vapor Pressure: 0Pa at 25℃
Boiling Point: 626.8±55.0 °C(Predicted)
PSA： 123.66000
Density: 1.29±0.1 g/cm3(Predicted)
LogP: 4.12760

461432-25-7 Relevant articles

Copper-Catalyzed Arylation of Benzylic C-H bonds with Alkylarenes as the Limiting Reagents

Zhang, Wen,Chen, Pinhong,Liu, Guosheng

, p. 7709 - 7712 (2017)

A novel copper-catalyzed arylation of be...

PREPARATION OF HIGHLY PURE AMORPHOUS DAPAGLIFLOZIN

-

Page/Page column 26, (2021/12/13)

A novel and improved process for the pre...

Novel preparation process of C-glucoside derivative

-

Paragraph 0098-0100, (2020/12/29)

The invention relates to a preparation m...

Preparation method of dapagliflozin

-

, (2020/05/05)

The invention relates to a preparation m...

Carbon-aryl glycoside SGLT-2 inhibitor precursor and synthesis method thereof

-

Paragraph 0026, (2019/03/28)

The invention relates to a plurality of ...

461432-25-7 Process route

: 461432-26-8,1373321-04-0
dapagliflozin

: 108-24-7
acetic anhydride

: 461432-25-7
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Conditions

Conditions	Yield
With pyridine; dmap; at 20 ℃; for 2h; Cooling with ice;	87%
With dmap; In dichloromethane; at 0 - 20 ℃;	71%
With dmap; In acetone; at 20 - 30 ℃; for 3h; Solvent; Temperature; Concentration;	6.4g
dapagliflozin; With dmap; In dichloromethane; at 25 - 30 ℃; for 0.333333h; acetic anhydride; In dichloromethane; at 25 - 30 ℃; for 4h;	128 g
With 4-methyl-morpholine; dmap; In dichloromethane; at 0 - 25 ℃; for 16h;	515 g

: 1118566-45-2,1373321-04-0
(1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol

: 108-24-7
acetic anhydride

: 461432-25-7
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Conditions

Conditions	Yield
With pyridine; dmap; In dichloromethane; at 20 ℃; for 2h;	71.3%
With pyridine; dmap; In dichloromethane; at 0 - 32 ℃; for 1.5h;	71%
With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 5 ℃;	10 g

461432-25-7 Upstream products

461432-28-0
methyl-2,3,4,6-tetra-O-acetyl-1-C-(2-chloro-4'ethoxydiphenylmethan-3yl)-α-D-glucopyranose
1118566-45-2
(1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
108-24-7
acetic anhydride
885069-29-4
1-(5-bromo-2-chlorophenyl)-1-methylethanol

461432-25-7 Downstream products

461432-26-8
dapagliflozin
1291094-21-7
acetic acid (2R,3R,4R,SS,6S)-3,4,5-triacetoxy-6-[3-(3-acetyl-4-hydroxybenzyl)-4-chloro-phenyl]-tetrahydro-pyran-2-ylmethyl ester
1318793-71-3
1-{4-chloro-3-[(dimethyl)(4-ethyloxyphenyl)methyl]phenyl}-1-deoxy-β-D-glucopyranose
864070-44-0
empagliflozin