Methyl 5-acetyl-2-phenylmethoxybenzoate

  • CAS:27475-09-8
  • purity:99%
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Reputable supplier selling Methyl 5-acetyl-2-phenylmethoxybenzoate 27475-09-8 with stock

  • Molecular Formula: C17H16O4
  • Molecular Weight: 284.312
  • Vapor Pressure: 0mmHg at 25°C 
  • Boiling Point: 443.482oC at 760 mmHg 
  • Flash Point: 196.816oC 
  • PSA: 52.60000 
  • Density: 1.167g/cm3 
  • LogP: 3.25480 

2-BENZYL-5-ACETYL METHYL SALICYLATE(Cas 27475-09-8) Usage

General Description

2-Benzyl-5-acetyl methyl salicylate, also known as "Benzyl salicylate," is a chemical compound commonly used in the fragrance and cosmetic industries. It is a colorless to pale yellow liquid with a sweet, slightly floral odor. This chemical is often added to perfumes, soaps, lotions, and other personal care products to impart a pleasant scent. It is also used as a flavoring agent in food products. Additionally, benzyl salicylate has been found to possess anti-inflammatory and analgesic properties, making it a valuable ingredient in topical pain relief products. However,

InChI:InChI=1/C17H16O4/c1-12(18)14-8-9-16(15(10-14)17(19)20-2)21-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3

27475-09-8 Relevant articles

A chromatography-free synthesis of racemic salbutamol hemisulfate

Vanoost, Agathe,Petit, Laurent

supporting information, (2020/06/30)

Our efforts to achieve an efficient synt...

Conformational control enabled by the fluorine gauche effect in a model of the β2-AR agonist salbutamol (Ventolin)

Teschers, Charlotte S.,Daniliuc, Constantin G.,Kehr, Gerald,Gilmour, Ryan

, p. 1 - 5 (2018/03/13)

The bronchodilator salbutamol adopts a c...

A multivalent approach to the discovery of long-acting β2- adrenoceptor agonists for the treatment of asthma and COPD

Jacobsen, John R.,Choi, Seok Ki,Combs, Jesse,Fournier, Eric J.L.,Klein, Uwe,Pfeiffer, Juergen W.,Thomas, G. Roger,Yu, Cecile,Moran, Edmund J.

scheme or table, p. 1213 - 1218 (2012/03/11)

A multivalent approach was applied to th...

PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES

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Page/Page column 25, (2012/03/27)

The present invention discloses a proces...

27475-09-8 Process route

estere metilico dell'acido 5-acetilsalicilico
16475-90-4

estere metilico dell'acido 5-acetilsalicilico

benzyl bromide
100-39-0

benzyl bromide

5-acetyl-2-benzyloxybenzoic acid methyl ester
27475-09-8

5-acetyl-2-benzyloxybenzoic acid methyl ester

Conditions
Conditions Yield
With potassium carbonate; In acetonitrile; at 85 ℃; for 9h;
100%
With potassium carbonate; In acetonitrile; at 75 ℃; for 16h;
100%
With potassium carbonate; In acetonitrile; for 24h;
96.6%
estere metilico dell'acido 5-acetilsalicilico; With potassium carbonate; In acetonitrile; for 0.75h; Inert atmosphere;
benzyl bromide; In acetonitrile; for 2h; Reflux; Inert atmosphere;
89%
With potassium carbonate; In butanone; for 8h; Heating / reflux;
71.4%
With potassium carbonate; In butanone; for 8h; Heating / reflux;
71.4%
With potassium carbonate; In butanone; for 8h; Heating / reflux;
71.4%
With potassium carbonate; In butanone; for 8h; Heating / reflux;
71.4%
With potassium carbonate; In butanone; for 8h; Heating / reflux;
71.4%
With potassium carbonate; In acetonitrile;
benzyl bromide
100-39-0

benzyl bromide

5-acetyl-2-benzyloxybenzoic acid methyl ester
27475-09-8

5-acetyl-2-benzyloxybenzoic acid methyl ester

Conditions
Conditions Yield
estere metilico dell'acido 5-acetilsalicilico; With potassium carbonate; In acetonitrile; for 0.166667h;
benzyl bromide; In methanol; at 85 ℃; for 9.25h;
100%

27475-09-8 Upstream products

  • 16475-90-4
    16475-90-4

    estere metilico dell'acido 5-acetilsalicilico

  • 100-44-7
    100-44-7

    benzyl chloride

  • 100-39-0
    100-39-0

    benzyl bromide

  • 78-93-3
    78-93-3

    butanone

27475-09-8 Downstream products

  • 201663-18-5
    201663-18-5

    5-acetyl-2-(benzyloxy)benzoic acid

  • 27475-14-5
    27475-14-5

    2-benzyloxy-5-(2-bromoacetyl)benzoic acid methyl ester

  • 63416-79-5
    63416-79-5

    5-(Dichloroacetyl)-2-(phenylmethoxy)benzoic acid, methyl ester

  • 67-56-1
    67-56-1

    methanol